Public Health Interventions to Reduce the Secondary Spread of Measles

Saturday, 3rd of October 2015 Print

Public Health Interventions to Reduce the Secondary Spread of Measles

Full text is at http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0078260/pdf/PubMedHealth_PMH0078260.pdf 

This extensive literature review, by the  Canadian Agency for Drugs and Technologies in Health, sought to answer the following research questions.

 

1.What is the clinical effectiveness associated with delivery of measles vaccine to susceptible measles contacts?

2.What is the clinical effectiveness associated with immunoglobulin

delivery to susceptible measles contacts?

3.What is the clinical effectiveness associated with quarantine of susceptible measles contacts?

4.What is the clinical effectiveness associated with isolation of communicable measles cases?

5.What is the clinical effectiveness of targeted measles vaccination activities during an outbreak?

 

“. . .The strongest available evidence relates to administration of measles-containing vaccine, with four of five included studies demonstrating a potential benefit (two reaching statistical significance) and the fifth small study (n = 6) demonstrating no benefit.”

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