Recent Technical Updates pg 22

USING COST-EFFECTIVENESS ANALYSIS TO SUPPORT RESEA ...

After 40 years of using the measles vaccine, it is still true today that millions of infants face a significant risk of death from measles, particularly in highly populated, low-income countries. The ...Source: Journal of Infectious Diseases

MEASLES VACCINATION COVERAGE ESTIMATES FROM SURVEY ...

Recent outbreaks of measles in low-income countries highlight that conventional vaccination coverage indicators do not adequately identify susceptible children. There is increasing interest in immune ...Source: BMC Public Health

SEROPREVALENCE SURVEY ON MEASLES, MUMPS, RUBELLA A ...

Persons working in medical facilities have a greater risk of being exposed to and acquiring measles, mumps, rubella, and varicella. Outbreaks of these diseases have been documented not only in the com ...Source: Epidemiology and Infeection

CROSS-SECTIONAL SURVEYS OF MEASLES ANTIBODIES IN T ...

A routine two-dose, single-antigen, live attenuated measles vaccine has been available for children administered the first dose in 8-12 months and the second dose at 7 years old in the Jiangsu provinc ...Source: PLoS One

DETECTION OF SERUM ANTIBODIES AGAINST MEASLES, MUM ...

Since 2004 the MMR vaccine, a live attenuated virus vaccine, has been included in the routine immunization program for children in Iran. All children are vaccinated with MMR at 12 months of age and re ...Source: Archives of Iranian Medicine

GLOBAL CONTROL AND REGIONAL ELIMINATION OF MEASLES ...

In 2010, the World Health Assembly established three milestones towards global measles eradication to be reached by 2015. Since that time, elimination goals have been set by member states of all six W ...Source: Weekly Epidemiological Record (WER)

PROGRESS TOWARD MEASLES ELIMINATION — WESTERN PA ...

In 2005, the World Health Organization (WHO) Regional Committee for the Western Pacific Region (WPR) resolved to eliminate measles in their region by 2012. Like the Global measles and Rubella/CRS ...Source: MMWR

MEASLES ELIMINATION: PROGRESS, CHALLENGES AND IMPL ...

In 2012, WHO and partners published the first global combined strategic plan for measles and rubella control and elimination. In this article, the authors review some principles of measles and rubella ...Source: Expert Review of Vaccines

CHANGING EPIDEMIOLOGY OF MEASLES IN AFRICA

In 2009, WHO African member states endorsed a goal of >98% reduction in measles mortality by 2012, compared with mortality in 2000, and an additional goal of regional measles elimination by 2020 wa ...Source: Journal of Infectious Diseases

EPIDEMIOLOGY OF MEASLES IN SOUTHWEST NIGERIA: AN A ...

The measles morbidity and mortality reduction programme of the WHO African region was adopted in Nigeria in 2005. The recommended strategies to achieve the programme goal included strengthening routin ...Source: Transactions of the Royal Society of Tropical Medicine and Hygiene

A 60-YEAR REVIEW ON THE CHANGING EPIDEMIOLOGY OF M ...

Using epidemiological data from Beijing, this article presents a unique story of five stages of measles elimination continuum namely Stage 1: Period prior to vaccination (1951–1965); S ...Source: BMC Public Health

MEASLES IN THE UNITED STATES, JANUARY 1–AUGUST 2 ...

During 2013, nearly two thirds of the measles cases reported in the US came from three outbreaks. In these outbreaks, transmission occurred after introduction of measles into communities with pockets ...Source: MMWR

PERSISTENCE OF VACCINE-INDUCED MEASLES ANTIBODY BE ...

In Africa, most countries administer a single dose of measles vaccine at age 9 months, complemented by mass vaccination of wider age groups in supplementary immunization activities (SIAs). In 2009, th ...Source: Journal of Infectious Diseases

SAFETY AND IMMUNOGENICITY OF EARLY MEASLES VACCINA ...

When considering protection of HIV-infected infants against measles one has to think of: a)optimal immunization age, b) the safety profile of measles vaccine among infants below 12 months of age, and ...Source: Journal of Infectious Diseases

ANTIBODY RESPONSE TO VACCINATION AMONG SOUTH AFRIC ...

Recent evidence indicates that HIV-exposed but uninfected infants (HEU) are at a higher risk of infectious morbidity and mortality than their HIV-unexposed, uninfected (HUU) peers. The underlying reas ...Source: Clinical and Vaccine Immunology

MEASLES VACCINE, HIV INFECTION, AND ANTIRETROVIRAL ...

Early in the human immunodeficiency virus (HIV) epidemic, it was recognized that measles can cause severe disease in HIV-infected children. Prior to highly active antiretroviral therapy (HAART), HIV-i ...Source: Journal of Infectious Diseases

MEASLES VACCINATION IN HIV-INFECTED CHILDREN: SYST ...

The World Health Organization (WHO) recommended in 2004 that, unless severely immunocompromised, HIV-infected infants should receive measles vaccine at 6 months of age, followed by another dose at 9 m ...Source: Journal of Infectious Diseases

The Genetic Basis For Interindividual Immune Respo ...

Measles elimination has failed primarily due to failure to vaccinate, but also in part due to vaccine failure, allowing the accumulation of susceptible individuals and the occurrence of outbreaks when ...Source: Expert Review of Vaccines

The Association of CD46, SLAM and CD209 Cellular R ...

While Measles Virus (MV) vaccine induces both humoral and CMI responses, the duration of protective immunity is shorter than that of acquired immunity during infection with wild-type virus. MV interac ...Source: Human Heredity

Vaccine Immunogenetics: Bedside to Bench to Popula ...

A variety of factors impact the heterogeneity of vaccine-induced immune responses. Some of these include gender, vaccine dose, the integrity of vaccine storage and cold chain maintenance, immune syste ...Source: Vaccine

Multigenic Control of Measles Vaccine Immunity Med ...

Given the multifactorial nature of diseases and the complexity of biological responses, it is highly likely that multigenic interactions affect vaccine response and immune outcomes, a process that is ...Source: Vaccine

CASE OF VACCINE-ASSOCIATED MEASLES FIVE WEEKS POST ...

In this report, the authors describe a case of measles-mumps-rubella (MMR) vaccine-associated measles illness that was positive by both PCR and IgM, five weeks after administration of the MMR vaccine. ...Source: Euro Surveillance and Outbreaks Report

LARGE ONGOING MEASLES OUTBREAK IN A RELIGIOUS COMM ...

A single dose of monovalent measles vaccine was included in the Dutch national immunization programme in 1976 for children aged 14 months. Since 1987, children have been offered vaccination against me ...Source: Euro Surveillance and Outbreaks Report

MEASLES — UNITED STATES, JANUARY 1–AUGUST 24, ...

Although measles elimination was declared in the United States in 2000, importation of measles cases continues to occur. In this article, CDC evaluated measles cases reported by 16 states during Janua ...Source: Morbidity and Mortality Weekly Report (MMWR)

MEASLES OUTBREAK IN SOUTH AFRICA: EPIDEMIOLOGY OF ...

In the World Health Organisation (WHO) African region, routine measles vaccination is offered at nine months of age but about 15% of children vaccinated at this age will not develop protective immune ...Source: PLoS One

IDENTIFYING HIGH-RISK AREAS FOR SPORADIC MEASLES O ...

Since 1995, several African countries have launched initiatives to eliminate measles, as recommended by the World Health Organization (WHO). These initiatives aim to: (i) achieve a coverage of&nb ...Source: Bulletin of the World Health Organization

MEASLES OUTBREAKS IN DISPLACED POPULATIONS: A REVI ...

Measles is an important public health concern during disasters involving massive population displacements who end up living in camps. Several outbreaks have been reported among refugees and other emer ...Source: BMC International Health and Human Rights

CHARACTERIZATION OF LARGE MUMPS OUTBREAK AMONG VAC ...

Sporadic mumps outbreaks in vaccinated populations have been attributed mainly to primary vaccine failure in individuals who had received one dose of MMR vaccine. More recently, the CDC reported a mum ...Source: Journal of Clinical Microbiology

MEASLES VACCINATION RESPONSE DURING KOSI FLOODS, B ...

With the changing population profile and communication situation following the floods, there arose a variety of related health issues which called for strategic health planning to prevent any large sc ...Source: Indian Paediatrics

WHO AND PARTNERS LAUNCH MEASLES VACCINATION IN CEN ...

The security situation in Central African Republic, Somalia and more recently South Sudan results in mass displacement of people. Such displacements of people cause over-crowding that is recipe for ou ...Source: WHO/Central Africa

TOP TEN HITS OF 2013 ON WWW.MEASLESUPDATES.ORG

Happy new year to all readers of this website. Its one year since this website was launched. As a new years tribute to our readers, we have examined the article hits.  I am now posting the most s ...Source: Measles and Rubella Initiative

Measles Imported by Returning U.S. Travellers Aged ...

The frequency of imported measles among children aged 6--23 months into the USA also suggests that parents and clinicians might not be aware of recommendations to administer MMR vaccine to children as ...Source: Morbidity and Mortality Weekly Report (MMWR)

Notes from the Field: Multiple Cases of Measles Af ...

Several countries have investigation guidelines for exposure to a single passenger with infectious measles aboard an aircraft. However, I know that air transport is not the most frequently used means ...Source: Morbidity and Mortality Weekly Report (MMWR)

Did Public Health Travel Advice Reach Euro 2012 Fo ...

Mass gatherings of this scale provide an environment for potential rapid spread of infectious diseases. Sporting events like national/international football tournaments, athletics events and national/ ...Source: Euro Surveillance and Outbreaks Report

Travelers Returning With Measles From Thailand To ...

Outbreaks of measles still occur repeatedly in Europe in many areas where vaccination coverage is not sufficiently high. In countries with high coverage, such as Finland (>95%), the small proportio ...Source: Euro Surveillance and Outbreaks Report

Comparing Measles With Previous Eradication Progra ...

The malaria, smallpox, and polio eradication initiatives were formally launched by the World Health Assembly in 1955, 1959, and 1988, respectively.Yaws and Guinea worm are two additional diseases that ...Source: Journal of Infectious Diseases

Synthesizing epidemiological and economic optima f ...

Traditionally, the main economic benefit of disease eradication was envisaged in terms of cessation of vaccination after interruption of infection. In a context of current focus on potential eliminati ...Source: Proceedings of the National Academy of Sciences, USA

Impact of Measles Elimination Activities on Immuni ...

At the 2010 World Health Assembly, milestones toward measles eradication were endorsed. However, the potential impacts on routine immunization services and the overall health system remains one of the ...Source: Journal of Infectious Diseases

How Can Measles Eradication Strengthen Health Care ...

 It is well established that many disease-control programs, including elimination and eradication initiatives, are delivered through a vertical approach, which can potentially hamper health syste ...Source: Journal of Infectious Diseases

A review of data needed to parameterize a dynamic ...

Although future measles incidence and disease burden cannot be known precisely, they can be projected by use of a dynamic model. Dynamic models incorporate transmission mechanisms and thus can describ ...Source: BioMed Central

Seroprevalence of Measles-, Mumps- and Rubella-Spe ...

Vaccinations with MMR within the first years of life may induce a shift of the incidence to older age groups. Therefore, sero-epidemiological surveys are highly important for the assessment of cu ...Source: PLoS One

Seroprevalence of measles and natural rubella anti ...

Since 2000, significant progress has been made to reduce the global burden of measles. Nowhere has this achievement been more pronounced than in Africa. As in the rest of the African Region, measles c ...Source: BioMed Central

Detection of serum antibodies against measles, mum ...

It has been estimated that even in countries where vaccination coverage approaches > 80%, a single dose of the vaccine leaves many children susceptible to measles. To eradicate measles and thus pre ...Source: Archives of Iranian Medicine

Balancing Evidence and Uncertainty When Considerin ...

Epidemic theory and empirical observation show that the average age of infection for a vaccine preventable disease conferring lifelong immunity is predominantly determined by the population birthrate, ...Source: PLoS One

Impact of birth rate, seasonality and transmission ...

Rubella vaccine has been licensed for nearly 50 years, is highly efficacious and available as combined measles-rubella (MR) or measles-mumps-rubella (MMR) vaccine. However, the challenge of preventing ...Source: Epidemiology and Infection

Implications of Spatially Heterogeneous Vaccinatio ...

Unless Rubella control measures are synchronized within a state or a broader region, there is a possible risk that the benefits of reduced disease incidence will be inequitably distributed, and potent ...Source: Journal of the Royal Society Interface

Rubella Epidemiology in Africa in the Pre-vaccine ...

Given that little is known about rubella in Africa, the authors provide an overview of published sero-prevalence surveys and analysis of surveillance and laboratory data as a baseline of prevaccine-er ...Source: Journal of Infectious Diseases

Early waning of maternal measles antibodies in era ...

International differences in the prevalence of maternal measles antibodies in infants have been described by Leuridan E (2003) and Caceres VM (2000). There also evidence that suggests that infant ...Source: BMJ

Effectiveness assessment of vaccination policy aga ...

In recent years, most individuals have acquired immunity to measles by vaccination. Because the antibody titer acquired by vaccination is low compared with that by natural infection, the possibility o ...Source: Environmental Health and Preventive Medicine

Timeliness Vaccination of Measles Containing Vacci ...

Receiving the vaccination within a recommended age period has become an important issue in many countries. Numerous studies suggested that a certain proportion of the target population lacking timely ...Source: PLoS One

Timeliness of Childhood Vaccinations in Kampala Ug ...

Over the last decade, Uganda like many other developing countries focused on promoting high vaccination coverage. However, some studies show that high vaccination coverage rates for individual vaccine ...Source: PLoS One

Ethnicity and Delay in Measles Vaccination in a Na ...

The vaccination coverage of measles in urban poor is low and continues to be a major public health concern in many countries. To solve this problem therefore requires a better understanding of the det ...Source: Tropical Medicine and Health

Subacute sclerosing panencephalitis: an update

SSPE was described first by Dawson in 1934, in an individual with rapidly progressive encephalitis. Later, in 1945, van Bogaert described another individual with the same clinical presentation but in ...Source: Development Medicine and Child Neurology

Epidemiology of Subacute Sclerosing Panencephaliti ...

Calculation of the risk of developing Subacute sclerosing panencephalitis (SSPE) after measles infection is complex, because information on both measles and SSPE incidences is required. The calculatio ...Source: PLoS One

Review of the effect of measles vaccination on the ...

When live measles vaccine became available in the early 1960s, the aetiology of SSPE was unknown. Once the association between measles virus and SSPE was established there were concerns that measles v ...Source: International Journal of Epidemiology

Sub-acute Sclerosing Panencephalitis: More Cases o ...

Analyses of measles virus sequences in brain tissue samples obtained from patients with SSPE have identified only wild-type measles virus, and the virus genotypes identified have been consistent with ...Source: Journal of Infectious Diseases

F-Actin Modulates Measles Virus Cell-Cell Fusion a ...

Previous studies have demonstrated that actin, a cellular cytoskeleton component, is packaged in the completed MV particles. Actin filaments were found to interact with the majority of MV structural p ...Source: Journal of Virology

Actin Filaments Disruption And Stabilization Affec ...

The actin network is primarily associated with mechanical stability, cell motility and cell contraction. It is also important for chromosome movement during mitosis and for internal transport, particu ...Source: Virology Journal

Sustained Autophagy Contributes To Measles Virus I ...

Autophagy is an evolutionarily conserved lysosomal dependent degradative pathway for recycling of long-lived proteins and damaged organelles. Autophagy is also an essential cellular response to fight ...Source: PLoS Pathogens

Sensitive Detection Of Measles Virus Infection In ...

Currently, humanized mouse systems are widely used as alternatives to non-human primate models, especially for the study of human-tropic infectious diseases such as HIV, human T cell leukemia virus, d ...Source: Frontiers in Microbiology