Recent Technical Updates pg 20

A SHORT CLINICAL REVIEW OF VACCINATION AGAINST MEA ...

Regardless of how individuals view vaccination, measles is one of the leading vaccine-preventable causes of morbidity and mortality among young children globally and is an important target for pu ...Source: Journal of the Royal Society of Medicine

A RANDOMIZED TRIAL OF A STANDARD DOSE OF EDMONSTON ...

Data from randomized trials have confirmed that measles vaccine has beneficial nonspecific effects, and therefore measles vaccine probably reduces severity or provide protection against infections oth ...Source: Journal of Infectious Diseases

MEASLES ANTIBODY LEVELS AFTER VACCINATION WITH EDM ...

It has recently been suggested to increase the age of vaccination in other regions when measles comes under control. An increase in age of primary measles vaccine (MV) could dramatically enlarge the n ...Source: Vaccine

INFLUENCE OF VACCINATION DOSE AND CLINICO-DEMOGRAP ...

The Japanese government established a 2-dose policy for a measles/rubella-combined (MR) vaccine in 2006: the first dose must be administered at the age of 1 year (MR-I) and the second at the age of 5& ...Source: Japanese Journal of Infectious Diseases

THE PATHOGEN- AND INCIDENCE-BASED DALY APPROACH: A ...

The disability-adjusted life year (DALY), a metric quantifying and combining the impact of premature death and non-fatal health outcomes resulting from disease, was jointly developed by the World Bank ...Source: PLoS One

IMPACT OF MEASLES NATIONAL VACCINATION COVERAGE ON ...

In order to gain insight into the overall impact of communicable diseases on population health in Europe and to support health policy-making, in 2009 the European Centre for Disease Prevention and Con ...Source: Vaccine

THE EFFECT OF MEASLES ON HEALTH-RELATED QUALITY OF ...

Previous measles outbreak reports focus on the epidemiology of the disease, rather than the overall disease burden in terms of health-related quality of life (HRQoL). The impact of infectious diseases ...Source: PLoS One

RELEVANCE OF A PRE-EXISTING MEASLES IMMUNITY PRIOR ...

Novel technologies in vaccinology are necessary to tackle major diseases of today, such as AIDS, malaria and tuberculosis. Reverse genetics permits the designing of viruses, to be used as vectors, in ...Source: Human Vaccine and Immunotherapeutics

PRIMING T-CELL RESPONSES WITH RECOMBINANT MEASLES ...

In a recombinant measles vaccine (rMV) vector, an antigen from another pathogen is incorporated into the measles genome. During the replication and transcription of rMV in a cell, the transgene is exp ...Source: Vaccine

IMMUNOGENICITY OF ATTENUATED MEASLES VIRUS ENGINEE ...

Reverse genetic techniques make insertion of foreign genes into MV genome possible and MV vectors expressing protective antigens have been tested in the development of vaccines against viral pathogens ...Source: Vaccine

IMMUNOGENICITY OF A RECOMBINANT MEASLES-HIV-1 CLAD ...

The characteristics of a live attenuated measles vaccine (MV) make it an attractive candidate vaccine vector. In turn, a reverse genetics system for MV has been established, allowing the production of ...Source: PLoS One

VACCINE ADVERSE EVENTS REPORTED DURING THE FIRST T ...

Vaccine safety surveillance and follow-up are central to address actual and perceived issues related to AEFI. However, such surveillance and follow-up infrastructure lags behind vaccine development in ...Source: Biomed Research International

MEASLES-CONTAINING VACCINES AND FEBRILE SEIZURES I ...

 In 2008, combination measles-mumps-rubella-varicella (MMRV) rapid cycle analysis of safety monitoring data detected a possible increased risk for seizures after receipt of MMRV. Subsequent ...Source: Pediatrics

IMMUNOGENICITY, IMMUNOLOGIC MEMORY, AND SAFETY FOL ...

Prior to highly active antiretroviral therapy (HAART), HIV-infected children had reduced response rates, lower antibody titers, and more rapid antibody decline following measles vaccination; lack of r ...Source: Journal of Infectious Diseases

IMMUNOGENICITY AND SAFETY OF MMRV AND PCV-7 ADMINI ...

In February 2000, a pneumococcal 7-valent conjugate vaccine (PCV-7) (Prevnar [Pfizer, Philadelphia, PA]) was licensed in the United States for use in infants and young children. The Advisory Committee ...Source: Pediatrics

VACCINE ADMINISTRATION AND THE DEVELOPMENT OF IMMU ...

Thrombocytopenia is an adverse event that has been associated with vaccine administration, and may limit vaccine use because information regarding which vaccines it may follow, its real incidence and ...Source: Human Vaccine and Immunotherapeutics

CROSS-SECTIONAL SURVEYS OF MEASLES ANTIBODIES IN T ...

Since 2007, changes in the epidemiological characteristics of measles had been observed in the Jiangsu province. At the time, the highest incidence of measles occurred in children less than 5 years ol ...Source: PLoS One

SEROPREVALENCE OF MEASLES- AND MUMPS-SPECIFIC IgG ...

To prevent hospital-acquired infections, physicians, healthcare workers, and healthcare students require immunity against vaccine-preventable diseases. The Advisory Committee on Immunization Practices ...Source: Japanese Journal of Infectious Diseases

SEROPREVALENCE OF ANTI-RUBELLA AND ANTI-MEASLES Ig ...

The World Health Organization (WHO) recommends that countries undertaking measles elimination should use the opportunity to eliminate rubella as well through the use of measles and rubella containing ...Source: PLoS One

SEROPREVALENCE OF MEASLES IgG AMONG HIV-1-INFECTED ...

Despite large gains towards measles eradication in Africa, over 50,000 measles-related deaths occur yearly; 2380 measles cases were reported in Kenya in 2012, more than twice as many as in 2010.& ...Source: International Journal of Infectious Diseases

SEROPOSITIVITY RATES FOR MEASLES, MUMPS, AND RUBEL ...

Maintaining population immunity against measles and rubella is important to prevent outbreaks. Currently, the Centers for Disease Control and Prevention Advisory Committee on Immunization Practices (A ...Source: Clinical and Vaccine Immunology

SEROPREVALENCE OF MEASLES-, MUMPS- AND RUBELLA-SPE ...

Vaccinations with MMR within the first years of life may induce a shift of the incidence of measles, rubella and mumps to older age groups. Realization of these potential effects may be delayed in Ger ...Source: PLoS One

WILD-TYPE MEASLES VIRUSES WITH NON-STANDARD GENOME ...

The genetic characterization of circulating wild-type measles viruses is a critical component of laboratory surveillance for measles. In combination with standard case classification, virologic survei ...Source: PLoS One

IMPLEMENTATION OF A NATIONAL MEASLES ELIMINATION P ...

Small and large outbreaks have occurred periodically in Iran. Two different measles genotypes have been reported from 2002-May 2010 in Iran. Genotype D4 was considered as the indigenous genotype befor ...Source: PLoS One

THE FIRST MEASLES OUTBREAK CAUSED BY IMPORTED GENO ...

Measles virus surveillance in China was initiated in 1993 and demonstrated that genotype H1 was the most dominant. Over the years, the measles virus genotype epidemiology has changed. For example geno ...Source: Japanese Journal of Infectious Diseases

MOLECULAR CHARACTERIZATION OF MEASLES VIRUSES THAT ...

The World Health Organization (WHO) currently recognizes 8 clades (A-H) within which are 24 genotypes of measles virus and one provisional genotype, d11. Genotype B3 is clearly the endemic genotype in ...Source: Virology Journal

TIMING OF MEASLES IMMUNIZATION AND EFFECTIVE POPUL ...

Immunization programs with carefully chosen evidence-based recommended times for vaccination are key to ensure that elimination of measles can be achieved. Such programs and their recommendations must ...Source: Pediatrics

TIMELINESS VACCINATION OF MEASLES CONTAINING VACCI ...

Receiving the vaccination within a recommended age period is an important program quality issue in many countries. Several studies suggest that a certain proportion of the target population lacking ti ...Source: PLoS One

TIMELINESS OF CHILDHOOD VACCINE UPTAKE AMONG CHILD ...

Timely receipt of vaccines is important because it ensures that the vaccinated child is protected from target diseases as early as possible. Delayed administration of vaccines can result in longer per ...Source: BMC Public Health

LESSONS AND CHALLENGES FOR MEASLES CONTROL FROM UN ...

Despite Malawi s measles control successes during the past 2 decades, a large outbreak occurred in 2010, with as many cases as in the 1980s. Response vaccinations were conducted in children 9–59 ...Source: Emerging Infectious Diseases

STRENGTHENING THE EXPANDED PROGRAMME ON IMMUNIZATI ...

The global effort to use vaccination as a public health intervention began when the World Health Organization (WHO) launched the Expanded Programme on Immunization (EPI) in 1974. Over the years there ...Source: PLoS Medicine

AN EVALUATION OF INFANT IMMUNIZATION IN AFRICA: IS ...

In response to challenges in global immunization, WHO and UNICEF set up the Global Immunization Vision and Strategy (GIVS) in 2003. The chief goal of GIVS was to reduce illness and death due to v ...Source: Bulletin of the WHO

CORRELATES OF COMPLETE CHILDHOOD VACCINATION IN EA ...

Despite the known health and economic benefits of childhood vaccinations, vaccination coverage in low-income countries vary widely. Increasing coverage of vaccines in the poorest countries to 90% in t ...Source: PLoS One

EFFECTS OF THE INTRODUCTION OF NEW VACCINES IN GUI ...

In 2008, Guinea-Bissau received support from GAVI to replace DTP with pentavalent vaccine, and yellow fever vaccine was introduced to be given together with measles vaccine. The introduction was accom ...Source: The Lancet Global Health

IMPACT OF THE INTRODUCTION OF NEW VACCINES AND VAC ...

Vaccines are costly and from many studies constitute a major burden for every immunization program. With the introduction of the Global Immunization, Vision and Strategy (GIVS), immunization coverage ...Source: BMC Cost Effectiveness and Resource Allocation

TOWARDS AMBIENT TEMPERATURE-STABLE VACCINES: THE I ...

Measles Vaccine (MV) is inherently labile, losing 50% potency after 1 h at 22–25 °C and almost 100% after 1 h at 37 °C. Reducing the moisture content in the vaccine, ...Source: Vaccine

VACCINE INSTABILITY IN THE COLD CHAIN: MECHANISMS, ...

The modern vaccine formulation development path from the discovery of an immunogen to a usable vaccine includes: (1) physical and chemical characterization of the antigenic component, (2) development ...Source: Vaccine

STABILIZATION OF MEASLES VIRUS FOR VACCINE FORMULA ...

Cost is a significant factor when considering improvement to vaccination programs in developing countries. One way to reduce vaccine costs is to generate vaccines with improved stability characteristi ...Source: Human Vaccine and Immunotherapeutics

LOCAL DISCREPANCIES IN MEASLES VACCINATION OPPORTU ...

In order to sustain gains in measles control and further reduce mortality, an understanding of whether each of these vaccination opportunities reaches children is essential. Vaccination coverage is th ...Source: BMC Public Health

CORRELATES OF COMPLETE CHILDHOOD VACCINATION IN EA ...

Current literature has identified several barriers to vaccinations in low income countries as lower parental education, lower maternal age, lower income, female gender of the child, traditional o ...Source: PLoS One

IMMUNIZATION COVERAGE: ROLE OF SOCIODEMOGRAPHIC VA ...

Immunization is often cited as being one of the greatest public health achievements of 20th century, but effective immunization requires population coverage levels of 90 to 95% depending upon the vacc ...Source: Advances in Preventive Medicine

FACTORS ASSOCIATED WITH NON-UTILIZATION OF CHILD I ...

The benefits of getting a child immunized are hardly questionable, yet studies have shown that, in many developing countries, a sizeable number of parents, usually belonging to socioeconomically disad ...Source: BMC Public Health

FACTORS ASSOCIATED WITH COMPLETE IMMUNIZATION COVE ...

Studies done in south and north Ethiopia showed that, mothers educational status, urban residence and perceived health care support are significantly associated with complete immunization coverage. St ...Source: BMC Public Health

IDENTIFYING HIGH-RISK AREAS FOR SPORADIC MEASLES O ...

A large outbreak of measles involving around 1,700 cases occurred in South Africa between 2003 and 2005 following its introduction from Mozambique. More recently, there was an outbreak between 2009 an ...Source: Bulletin of the World Health Organization

SEROPREVALENCE OF MEASLES IGG AMONG HIV-1-INFECTED ...

Currently, there is little information on measles seroprevalence among HIV-infected or HIV-uninfected adults in developing countries. Few non-Western data exist and results vary: in Iran, 45% of previ ...Source: International Journal of Infectious Diseases

EFFECT OF MULTIVITAMIN SUPPLEMENTATION ON MEASLES ...

Immunization and nutritional interventions are the foundation for most child health programs worldwide, yet limited data are available on the interaction between vaccine responses and nutrition.  ...Source: Clinical and Vaccine Immunology

FACTORS AFFECTING THE INFANT ANTIBODY RESPONSE TO ...

Despite the availability of a stable and effective vaccine, measles outbreaks are still an important concern in Eastern and Southern Africa.  Previous studies have suggested that induction of pro ...Source: BMC Public Health

GLOBAL CONTROL AND REGIONAL ELIMINATION OF MEASLES ...

In 2010, the World Health Assembly established three milestones towards global measles eradication to be reached by 2015. Since that time, elimination goals have been set by member states of all six W ...Source: Morbidity and Mortality Weekly Report (MMWR)

PROGRESS TOWARD MEASLES ELIMINATION — EASTERN ME ...

In this report, the authors report that since EMR countries first resolved to eliminate measles, substantial progress has been made. In the period 2000–2012, the report documents that measles in ...Source: Morbidity and Mortality Weekly Report (MMWR)

PROGRESS TOWARD MEASLES PRE-ELIMINATION IN AFRICAN ...

In 2008, the 46 member states of the World Health Organization (WHO) African Region (AFR) adopted a measles pre-elimination goal to reach by the end of 2012. This report documents that despite substan ...Source: Morbidity and Mortality Weekly Report (MMWR)

PROGRESS TOWARD MEASLES ELIMINATION — WESTERN PA ...

In 2012, the WPR Regional Committee reaffirmed its commitment to eliminate measles and urged member states to interrupt all residual endemic measles virus transmission as rapidly as possible. To achie ...Source: Morbidity and Mortality Weekly Report (MMWR)

IMPACT OF MEASLES NATIONAL VACCINATION COVERAGE ON ...

Several studies have reported on the relationship between the measles incidence, or risk of measles outbreaks, and the vaccination coverage of a population. However, no reports have documented the rel ...Source: Vaccine

VACCINE-ASSOCIATED MEASLES IN THE LOW-INCIDENCE CO ...

Over the past decade, the incidence of measles in Korea is reported to have decreased from over 60 cases per 100,000 population to less than 1 case per 100,000. In the same period, the proportion of c ...Source: Japanese Journal of Infectious Diseases

IDENTIFYING HIGH-RISK AREAS FOR SPORADIC MEASLES O ...

Spatial analysis can be an important epidemiological tool for detecting and predicting patterns of disease spread. In situations where population-wide interventions are too expensive or are ineff ...Source: Bulletin of the WHO

MEASLES OUTBREAK IN SOUTH AFRICA: EPIDEMIOLOGY OF ...

There is a dearth of information about the possible causes of recurrent measles outbreaks and little data on the effectiveness of outbreak-response vaccination in African countries. In this report, th ...Source: PLoS One

CAN MEASLES BE ERADICATED GLOBALLY?

As we come to terms with the passing on, of Ciro A. de Quadros, it is befitting to share the thoughts of a global public health icon. To some of us who worked with Ciro A. de Quadros, we shall ever re ...Source: Bulletin of the World Health Organization

MEASLES ERADICATION IN THE AMERICAS: PROGRESS TO D ...

In the increasingly congested public health practice environment, it is not uncommon that we achieve great milestones,  but never get time to publish in peer reviewed journals.  Ciro A. de Q ...Source: Journal of Infectious Diseases

INTEGRATING MEASLES AND RUBELLA SURVEILLANCE: THE ...

In line with the measles and Rubella/CRS elimination strategic plan, integrating case-based surveillance systems for measles and rubella is a vital element. As the we tend towards measles and rubella ...Source: Journal of Infectious Diseases

MONITORING MEASLES ERADICATION IN THE REGION OF TH ...

Monitoring vaccination coverage and indeed an effective surveillance system for measles are critical elements of measles elimination programming. Assuring that reported vaccination coverage (routine o ...Source: Journal of Infectious Diseases

MEASLES — UNITED STATES, JANUARY 1–MAY 23, 201 ...

Measles elimination has been maintained in the United States since elimination was declared almost 15 years ago. However, approximately 20 million cases of measles occur each year globally, and import ...Source: MMWR