Measles Virus Infection Among Vaccinated and Unvaccinated Children in Nigeria.

Wednesday, 27th of June 2018

Measles Virus Infection Among Vaccinated and Unvaccinated Children in Nigeria. 

Authors Faneye Adedayo O. Adeniji Johnson A. Olusola Babatunde A. Motayo Babatunde O. Akintunde Grace B.Published Online:2 Jul 2015

https://doi.org/10.1089/vim.2014.0118

Abstract

This study investigated measles infection in vaccinated and unvaccinated children presenting with fever and maculopapular rash during measles outbreaks in the southern and western states of Nigeria. Measles an acute viral illness caused by a virus in the family Paramyxoviridae is a vaccine-preventable disease. Measles outbreak is common in Nigeria despite the national immunization program. Children presenting with symptoms of measles infection in general hospitals and health centers in the states of southern and western Nigeria were recruited for this study. Vaccination history clinical details and 5 mL of blood were obtained from the children. Their sera samples were screened for specific immunoglobulin M antibodies to measles virus. Of 234 children tested (124 [53.2%] female) 133 (56.8%) had previously been vaccinated against measles virus while 93 (39.7%) had not been vaccinated. Vaccination information for eight children could not be retrieved. One hundred and forty-three (62.4%) had measles IgM antibodies. Of these 79 (55.3%) had been vaccinated for measles while 65 (44.7%) had not. Despite the ongoing vaccination program in Nigeria a high number of children are still being infected with measles despite their vaccination status. Therefore there is need to identify the reason for the low level of vaccine protection.

 

Faneye A. O. Adeniji J. A. Olusola B. A. Motayo B. O. & Akintunde G. B. (2015). Measles Virus Infection Among Vaccinated and Unvaccinated Children in Nigeria. Viral Immunology 28(6) 304–308. https://doi.org/10.1089/vim.2014.0118