Long-term Sero-protection Rates Following One-dose Measles (9-month) and One-dose MMR Vaccination (15 months) in Indian Children.

Friday, 2nd of March 2018 Print

Indian Pediatr. 2018 Feb 9. pii: S097475591600116. [Epub ahead of print]

Long-term Sero-protection Rates Following One-dose Measles (9-month) and One-dose MMR Vaccination (15 months) in Indian Children.

Hansashree P1 Verma S2 Rawat A1 Sankhyan N1 Bharti B1.

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Abstract

OBJECTIVE:

To find out seropositivity rates at 4-6 and 9-12 years of age; among those who received one-dose measles at 9 months and one-dose MMR at 15 months of age.

METHODS:

80 healthy children (53 males) at 4-6 or 9-12 years of age attending outpatient department for vaccination were enrolled. Antibody titers were estimated using commercially available quantitative-IgG ELISA kits.

RESULTS:

The seropositivity rates against measles mumps rubella were 80% (40/50) 86% (43/50) and 96% (48/50) respectively at 4-6 years and 83.3% (25/30) 96.7% (29/30) and 96.7% (29/30) respectively at 9-12 years of age.

CONCLUSION:

Single dose of rubella vaccine seems to provide adequate long-term protection; however measles vaccine requires more doses for similar protection.

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