Estimated economic impact of vaccinations in 73 low- and middle-income countries 2001-2020.

Tuesday, 31st of October 2017 Print

Bull World Health Organ. 2017 Sep 1;95(9):629-638. doi: 10.2471/BLT.16.178475. Epub 2017 Jun 27.

Estimated economic impact of vaccinations in 73 low- and middle-income countries 2001-2020.


Ozawa S1 Clark S2 Portnoy A3 Grewal S4 Stack ML5 Sinha A6 Mirelman A7 Franklin H6 Friberg IK8 Tam Y2 Walker N2 Clark A9 Ferrari M10 Suraratdecha C11 Sweet S12 Goldie SJ12 Garske T13 Li M14 Hansen PM15 Johnson HL14 Walker D16.

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To estimate the economic impact likely to be achieved by efforts to vaccinate against 10 vaccine-preventable diseases between 2001 and 2020 in 73 low- and middle-income countries largely supported by Gavi the Vaccine Alliance.


We used health impact models to estimate the economic impact of achieving forecasted coverages for vaccination against Haemophilus influenzae type b hepatitis B human papillomavirus Japanese encephalitis measles Neisseria meningitidis serogroup A rotavirus rubella Streptococcus pneumoniae and yellow fever. In comparison with no vaccination we modelled the costs - expressed in 2010 United States dollars (US$) - of averted treatment transportation costs productivity losses of caregivers and productivity losses due to disability and death. We used the value-of-a-life-year method to estimate the broader economic and social value of living longer in better health as a result of immunization.


We estimated that in the 73 countries vaccinations given between 2001 and 2020 will avert over 20 million deaths and save US$ 350 billion in cost of illness. The deaths and disability prevented by vaccinations given during the two decades will result in estimated lifelong productivity gains totalling US$ 330 billion and US$ 9 billion respectively. Over the lifetimes of the vaccinated cohorts the same vaccinations will save an estimated US$ 5 billion in treatment costs. The broader economic and social value of these vaccinations is estimated at US$ 820 billion.


By preventing significant costs and potentially increasing economic productivity among some of the worlds poorest countries the impact of immunization goes well beyond health.


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