Missed Opportunities for Measles Mumps Rubella Vaccination Among Departing U.S. Adult Travelers Receiving Pretravel Health Consultations.

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Ann Intern Med. 2017 May 16. doi: 10.7326/M16-2249. [Epub ahead of print]

Missed Opportunities for Measles Mumps Rubella Vaccination Among Departing U.S. Adult Travelers Receiving Pretravel Health Consultations.

Hyle EP¹ Rao SR¹ Jentes ES¹ Fiebelkorn AP¹ Hagmann SHF¹ Walker AT¹ Walensky RP¹ Ryan ET¹ LaRocque RC¹.

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Abstract

Background:

Measles outbreaks continue to occur in the United States and are mostly due to infections in returning travelers.

Objective:

To describe how providers assessed the measles immunity status of departing U.S. adult travelers seeking pretravel consultation and to assess reasons given for nonvaccination among those considered eligible to receive the measles mumps rubella (MMR) vaccine.

Design:

Observational study in U.S. pretravel clinics.

Setting:

24 sites associated with Global TravEpiNet (GTEN) a Centers for Disease Control and Prevention-funded consortium.

Patients:

Adults (born in or after 1957) attending pretravel consultations at GTEN sites (2009 to 2014).

Measurements:

Structured questionnaire completed by traveler and provider during pretravel consultation.

Results:

40 810 adult travelers were included; providers considered 6612 (16%) to be eligible for MMR vaccine at the time of pretravel consultation. Of the MMR-eligible 3477 (53%) were not vaccinated at the visit; of these 1689 (48%) were not vaccinated because of traveler refusal 966 (28%) because of provider decision and 822 (24%) because of health systems barriers. Most MMR-eligible travelers who were not vaccinated were evaluated in the South (2262 travelers [65%]) or at nonacademic centers (1777 travelers [51%]). Nonvaccination due to traveler refusal was most frequent in the South (1432 travelers [63%]) and in nonacademic centers (1178 travelers [66%]).

Limitation:

These estimates could underrepresent the opportunities for MMR vaccination because providers accepted verbal histories of disease and vaccination as evidence of immunity.

Conclusion:

Of U.S. adult travelers who presented for pretravel consultation at GTEN sites 16% met criteria for MMR vaccination according to the providers assessment but fewer than half of these travelers were vaccinated. An increase in MMR vaccination of eligible U.S. adult travelers could reduce the likelihood of importation and transmission of measles virus.

Primary Funding Source:

Centers for Disease Control and Prevention National Institutes of Health and the Steve and Deborah Gorlin MGH Research Scholars Award.