MEASLES, MUMPS, AND RUBELLA

Monday, 26th of May 2014

[source]Clinical Obstetrics and Gynaecology[|source]

In this report, the authors present a review of measles, mumps and rubella vaccine use and especially implications in pregancy. The report doccumenta that a) Measles exposure during pregnancy may cause adverse maternal and fetal effects before recommending Immune globulin prophylaxis for non-immune, exposed obstetric patients as long as treatment is received no more than six days after exposure; b) Spontaneous abortion is likely to occur in 27% of pregnant women exposed to mumps during their first trimester compared to 13% of controls and; c) Rubella infection in pregancy can cause transplacental passage of the virus to the embryo/fetus during maternal viremia causing the dvastatingg CRS before documenting that frequency and severity of CRS decreases as gestation progresses. Paper concludes that accidental MMR vaccination of pregant women is not known to cause maternal or fetal complications. More details are accessible at: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334858/

 

 ABSTRACT

Measles, mumps, and rubella are viral diseases that may adversely affect non-immune pregnant women and their fetuses/neonates. Prevention of these diseases and their complications can be achieved through measles-mumps-rubella (MMR) vaccination prior to pregnancy. The vaccine is contraindicated during pregnancy because it contains live, attenuated viruses that pose a theoretical risk to the fetus. However, accidental receipt of MMR vaccination is not known to cause maternal/fetal complications. MMR immunization is recommended to non-immune obstetric patients upon completion or termination of pregnancy.