SUBACUTE SCLEROSING PANENCEPHALITIS PRESENTING AS NEUROMYELITIS OPTICA

Tuesday, 16th of July 2013 Print
[source]BMJ Case reports[|source]

In this case report, the authors document clinical progress in a child in which there were atypical features simulating that of neuromyelitis optica but as the disease progressed, characteristic myoclonic jerks and EEG findings alongwith cerebrospinal fluid serology confirmed the diagnosis of subacute sclerosing panencephalitis (SSPE). This case confirms that the initial manifiestations of SSPE can be quiet varied. However, as SSPE progresses, typical manifestations lead to diagnosis. More details about the case are available at:  http://casereports.bmj.com/content/2012/bcr-2012-006764.long

 

 

Abstract

Subacute sclerosing panencephalitis (SSPE) is a slowly progressing inflammatory and degenerative disorder of the brain caused by a mutant measles virus. The diagnosis of SSPE is based on characteristic clinical and EEG findings (periodic complexes) and demonstration of elevated antibody titres against measles in cerebrospinal fluid. SSPE can have atypical clinical features at the onset. The authors here report a case of a 3-year-old child who presented with vision loss followed 15 months later by quadriparesis with bladder involvement. These clinical features resembled that of neuromyelitis optica. However, as the disease progressed, appearance of myoclonic jerks, periodic discharges on EEG and positive cerebrospinal fluid serology for measles led to the final diagnosis of SSPE.

Special Postings

What's New

Monday, 9th of March 2020

Monday, 9th of March 2020

Monday, 9th of March 2020

Monday, 9th of March 2020

Monday, 9th of March 2020
;

Highly Accessed

Website Views

47457734

External Links