ATYPICAL CLINICAL COURSE SUBACUTE SCLEROSING PANENCEPHALITIS PRESENTING AS ACUTE ENCEPHALITIS.

Tuesday, 16th of July 2013 Print
[source]Journal of Paediatric Neurosciences[|source]

SSPE should be considered when a patient with measles history is admitted because of atypical clinical features like loss of consciousness, acute partial-generalized convulsion, acute-subacute coma, visual loss, ataxia, and hemiparesis. In this case report, the authors describe a 14-year-old boy that was referred with fatigue, gait instability before progressing to loss of consciousness with a history of measles at age 3 years. This article emphasizes the importance of serial electroencephalogram (EEG) in SSPE diagnosis. If interested in atypical presentation of SSPE, then read details available at:  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519069/

 

 

Abstract

We report a 14-year-old boy who presented with loss of consciousness and gait instability. The electroencephalogram (EEG) showed generalized slowing with irregular activity and cerebral magnetic imaging revealed asymmetrical nonspecific signals on basal ganglia. His second electroencephalogram revealed periodical generalized high-voltage slow wave complexes which did not disappear with diazepam induction. Subacute sclerosing panencephalitis (SSPE) was considered and the diagnosis was confirmed with the identification of measles antibodies in cerebrospinal fluid. Our findings show that SSPE should be in mind in the differential diagnosis of meningoencephalitis and acute disseminated encephalomyelitis and highlight the significance of EEG in the diagnosis of unidentified cases.

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