BIOLOGICAL FEASIBILITY OF MEASLES ERADICATION

Thursday, 14th of February 2013 Print
[source]Journal of Infectious Diseases[|source]

Full text on the biological criteria for measles eradication are laid down. The article also articulates the challenges of logistics, political committment, and financing of such a goal is available at

http://jid.oxfordjournals.org/content/204/suppl_1/S47.full

Abstract

Recent progress in reducing global measles mortality has renewed interest in measles eradication. Three biological criteria are deemed important for disease eradication: (1) humans are the sole pathogen reservoir; (2) accurate diagnostic tests exist; and (3) an effective, practical intervention is available at reasonable cost. Interruption of transmission in large geographical areas for prolonged periods further supports the feasibility of eradication. Measles is thought by many experts to meet these criteria: no nonhuman reservoir is known to exist, accurate diagnostic tests are available, and attenuated measles vaccines are effective and immunogenic. Measles has been eliminated in large geographical areas, including the Americas. Measles eradication is biologically feasible. The challenges for measles eradication will be logistical, political, and financial.

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